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Patch Clamp Technique
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Help: Flash EOL

Flash content link

Animation: https://vlab.amrita.edu/repo/BIOTECH/NEO/PatchClamp/index.swf

Simulation: https://vlab.amrita.edu/repo/BIOTECH/NEO/Neuron_simulator/Neuron_Sim3.swf

 

                    Unfortunately, this Virtual Lab requires Adobe Flash player.  Please see additional information if this does not work on your computer

 

• For Google Chrome - https://support.google.com/chrome/answer/6258784?co=GENIE.Platform%3DDesktop&hl=en

• For Microsoft Edge - https://support.microsoft.com/en-in/help/4532571/microsoft-edge-turn-on-flash 

• For Mozilla Firefox - https://support.mozilla.org/en-US/kb/install-flash-plugin-view-videos-animations-games

 

On GNU/Linux machines, please see appropriate online help. For example, 

 

on Ubuntu - https://help.ubuntu.com/stable/ubuntu-help/net-install-flash.html.en 

on Fedora - https://docs.fedoraproject.org/en-US/quick-docs/using-adobe-flash/

 

  1.  Animation:

The animation controls include - fullscreen view, - return to previous scene, pause, play and next scene buttons.

 

  1. Simulator:

           Click on the “Simulator icon”   to launch the simulator.

 

Making the Hodgkin-Huxley Neuron Spike:

 

Detailed simulator has been implemented as a separate lab (Neuron Simulator Lab). The lab uses a graphical web-based Neuron simulator and models a section of excitable neuronal membrane using the Hodgkin-Huxley equations. Various experiments will deal with the several parameters of Hodgkin-Huxley equations and will model resting and action potentials, voltage and current clamp, pharmacological effects of drugs that block specific channels etc.

 

For detailed understanding please click on the respective hyperlinks provided below.

 

1) Modeling the sodium ion channel and its effects on neural signaling

 

2) Modeling the delayed rectifier potassium channels

 

Cite this Simulator:

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