Tasks to be performed
- Perform two sample DNA pairwise sequence alignment in R programming platform.
- Align FASTA formatted Keratin and Actin protein sequences of Homosapiens and Macaca mulattas, using R programming find out the scores and similarity index.
- You are provided with DNA sequence of a wild type mice and a mutant mice. With the knowledge of sequence alignment, find the match/mismatch score. Use R programming platform to find the matrix score.
Mutant type
5’-UGUACAUGAUGAAAACAGUCUCCCUCUUCUGAAUCUCGCUGAGGAA ACUGCACGUCACCCUCCUGAAA-3’
Wild type
5’-UGUACAUGAUGAAGUCAUAGCGAACGGAGAAGGGCCGGCUGAGGAAACUGCACGUCACCCUCCUGAAA-3’