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Understanding first spike latency - current relationship



Journal articles


  1. Furukawa S, Middlebrooks JC (2002). Cortical representation of auditory space: information-bearing features of spike patterns. J Neurophysiol., Apr;87(4):1749-62.
  2. Gawne TJ, Kjaer TW, Richmond BJ (1996). Latency: another potential code for feature binding in striate cortex. J Neurophysiol. Aug;76(2):1356-60.
  3. Hodgkin, AL. & Huxley, AF. (1952e). Propagation of electrical signals along giant nerve fibers. Proc R SocLond B Biol Sci. 140(899): 177-183. 
  4. Hodgkin, AL, Katz, B. The effect of sodium ions on the electrical activity of the giant axon of the squid. J Physiol (Lond) 108,37–77,1949.
  5. Marmont, G. (1949) Studies on the axon Membrane; a new method. J Cell Physiol. 1949 Dec;34(3):351-82.
  6. Panzeri S, Petersen RS, Schultz SR, Lebedev M, Diamond ME (2001). The role of spike timing in the coding of stimulus location in rat somatosensory cortex. Neuron. Mar;29(3):769-77.
  7. Reich, DS.,Mechler, F., and Victor, J.D. (2001) Independent and redundant information in nearby cortical neurons. Science 294, 2566-2568.




  1. BertilHille .Ionic channels of excitable membrane,2nd Ed. Sinauer Associates Inc, Sunderland, Massachusetts,1992.
  2. Kandel,ER.,J.H.Schwartz and T.M.Jessell.Principles of neural science,4thEd. McGraw-Hill Companies, Inc , New York, 2000.
  3. ArelesMolleman .Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology,J. Wiley, 2002.



  1. Electrophysiology  - http://www.acnp.org/g4/GN401000005/CH005.html
  2. Current clamp technique - http://vlab.amrita.edu/?sub=3&brch=43&sim=132&cnt=1379
  3. Action Potentials from Squid feat. Alan Hodgkin  -http://www.youtube.com/watch?v=k48jXzFGMc8

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