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Current Clamp protocol




  1. Cole, K.S. (1949) Dynamic electrical characteristics of the squid axon membrane. Arch. Sci. Phtsiol.3:253-25.
  2. Hodgkin, A.L. & Huxley, A.F. (1952a). Currents carried by the sodium and potassium ion through the membrane of the giant axon of Loligo. J. Physiol. 116(4): 449-472.
  3. Hodgkin, A.L. & Huxley, A.F. (1952c). The dual effect of membrane potential on sodium conductance in the giant axon of Loligo. J. Physiol. 116(4): 497-506.
  4. Hodgkin, A.L. & Huxley, A.F. (1952e). Propagation of electrical signals along giant nerve fibers. Proc R Soc Lond B Biol Sci. 140(899): 177-183. 
  5. Hodgkin, AL, Katz, B. The effect of sodium ions on the electrical activity of the giant axon of the squid. J Physiol (Lond) 108,37–77,1949.
  6. Marmont, G. (1949) Studies on the axon Membrane; a new method. J Cell Physiol. 1949 Dec;34(3):351-82.
  7. Rashevsky, N. (1938/1948 2nd ed.)  Mathematical Biophysics:Physico-Mathematical Foundations of Biology. Univ. of Chicago Press. : Chicago Press. theoretical biology
  8. Warren McCulloch and Walter Pitts. (1943)  A Logical Calculus of Ideas Immanent in Nervous Activity,  Bulletin of Mathematical Biophysics 5:115-133.



  1. Bertil Hille .Ionic channels of excitable membrane,2nd Ed. Sinauer Associates Inc, Sunderland, Massachusetts,1992.
  2. Kandel,ER.,J.H.Schwartz and T.M.Jessell.Principles of neural science,4thEd. McGraw-Hill Companies, Inc , New York, 2000.



  1. Intracellular recording -  http://www.scholarpedia.org/article/Intracellular_recording
  2. Current clamp technique - http://vlab.amrita.edu/?sub=3&brch=43&sim=132&cnt=1379
  3. Action Potentials from Squid feat. Alan Hodgkin  - http://www.youtube.com/watch?v=k48jXzFGMc8

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